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Few people realize that prescription drugs have become a leading cause of death, disease, and disability. Adverse reactions to widely used drugs, such as psychotropics and birth control pills, as well as biologicals, result in FDA warnings against adverse reactions.

The Risks of Prescription Drugs describes how most drugs approved by the FDA are under-tested for adverse drug reactions, yet offer few new benefits. Drugs cause more than 2.2 million hospitalizations and 110,000 hospital-based deaths a year. Serious drug reactions at home or in nursing homes would significantly raise the total. Women, older people, and people with disabilities are least used in clinical trials and most affected.

Health policy experts Donald Light, Howard Brody, Peter Conrad, Allan Horwitz, and Cheryl Stults describe how current regulations reward drug companies to expand clinical risks and create new diseases so millions of patients are exposed to unnecessary risks, especially women and the elderly. They reward developing marginally better drugs rather than discovering breakthrough, life-saving drugs.

The Risks of Prescription Drugs tackles critical questions about the pharmaceutical industry and the privatization of risk. To what extent does the FDA protect the public from serious side effects and disasters? What is the effect of giving the private sector and markets a greater role and reducing public oversight? This volume considers whether current rules and incentives put patients' health at greater risk, the effect of the expansion of disease categories, the industry's justification of high U.S. prices, and the underlying shifts in the burden of risk borne by individuals in the world of pharmaceuticals. Chapters cover risks of statins for high cholesterol, SSRI drugs for depression and anxiety, and hormone replacement therapy for menopause. A final chapter outlines six changes to make drugs safer and more effective.

Suitable for courses on health and aging, gender, disability, and minority studies, this book identifies the Risk Proliferation Syndrome that maximizes the number of people exposed to these risks.

Additional Columbia / SSRC books on the privatization of risk and its implications for Americans:

Bailouts: Public Money, Private ProfitEdited by Robert E. Wright

Disaster and the Politics of InterventionEdited by Andrew Lakoff

Health at Risk: America's Ailing Health System-and How to Heal ItEdited by Jacob S. Hacker

Laid Off, Laid Low: Political and Economic Consequences of Employment InsecurityEdited by Katherine S. Newman

Pensions, Social Security, and the Privatization of RiskEdited by Mitchell A. Orenstein

The pharmaceutical industry is praised as a world leader in high technology innovation and the creator of products that increase both longevity and quality of life for people throughout the world. At the same time, the industry is also criticized for its marketing and pricing practices and for its apparent anticompetitive responses to generic competition. Even its research and development priorities are criticized as being too closely driven by the goal of maximizing shareholder value, rather than the health of the public. Unfortunately, many of the critics of the industry fail to understand the complexities of the industry and its role in the nations healthcare system. This book uses the tools of economic analysis to explore the conflicting priorities and aims of the pharmaceutical industry, from both an American and worldwide perspective.This is the second edition of a uniquely comprehensive and balanced discussion of pharmaceutical policy issues. All the chapters of the former edition have been fully re-written and extensively updated.In addition, the book includes six new chapters on emerging topics such as the broadened role of FDA regulations and the increasing diversity of the industry. An entire chapter is devoted to the biotechnology industry and one to alternative medicines, often called "nutraceuticals." Another new chapter discusses segments of the industry that specialize in particular activities including generic drugs and drug delivery systems. The recent controversial expansion of Medicare to cover outpatient drugs is discussed in depth. The introduction is also updated to address the volatile pace of pharmaceutical innovation and how the pharmaceutical industry has responded to the emergence of managed care.

Americans praise medical technology for saving lives and improving health. Yet, new technology is often cited as a key factor in skyrocketing medical costs.

This volume, second in the Medical Innovation at the Crossroads series, examines how economic incentives for innovation are changing and what that means for the future of health care.

Up-to-date with a wide variety of examples and case studies, this book explores how payment, patent, and regulatory policies--as well as the involvement of numerous government agencies--affect the introduction and use of new pharmaceuticals, medical devices, and surgical procedures.

The volume also includes detailed comparisons of policies and patterns of technological innovation in Western Europe and Japan.

This fact-filled and practical book will be of interest to economists, policymakers, health administrators, health care practitioners, and the concerned public.

This text provides a straightforward explanation of the essential pharmacoeconomics topics outlined by The Accreditation Council for Pharmacy Education (ACPE). It defines terminology used in research and covers the application of economic-based evaluation methods to pharmaceutical products and services, making it perfect for the student or practitioner who is unfamiliar with "pharmacoeconomics." Readers will find examples of how pharmacoeconomic evaluations relate to decisions that affect patient care and health-related quality of life. Understanding these principles will help you assess published research aimed at improving clinical and humanistic outcomes based on available resources. You’ll Find These Helpful Features Inside— · Composite research articles that include the positives and negatives found in published research which will help you learn to evaluate literature and to interpret and determine the usefulness of pharmacoeconomic research articles. · Composite worksheets increase your comprehension of just-read articles. · Examples provide and reinforce relevant illustrations of chapter content. · Questions/Exercises at the end of each chapter assess your understanding of the key concepts. · Common Equations that are critical to the subject are presented, with multiple example calculations that clearly demonstrate the use of these equations

We like to imagine that medicine is based on evidence and the results of fair testing and clinical trials. In reality, those tests and trials are often profoundly flawed. We like to imagine that doctors who write prescriptions for everything from antidepressants to cancer drugs to heart medication are familiar with the research literature about a drug, when in reality much of the research is hidden from them by drug companies. We like to imagine that doctors are impartially educated, when in reality much of their education is funded by the pharmaceutical industry. We like to imagine that regulators have some code of ethics and let only effective drugs onto the market, when in reality they approve useless drugs, with data on side effects casually withheld from doctors and patients.
All these problems have been shielded from public scrutiny because they're too complex to capture in a sound bite. But Ben Goldacre shows that the true scale of this murderous disaster fully reveals itself only when the details are untangled. He believes we should all be able to understand precisely how data manipulation works and how research misconduct in the medical industry affects us on a global scale.
With Goldacre's characteristic flair and a forensic attention to detail, Bad Pharma reveals a shockingly broken system and calls for regulation. This is the pharmaceutical industry as it has never been seen before.

The most up-to-date, comprehensive, and authoritative pharmacology text in health medicine

Enhanced by more than three hundred illustrations -- many in full color

Organized to reflect the syllabi in many pharmacology courses and in integrated curricula, Basic & Clinical Pharmacology, 12e covers the important concepts students need to know about the science of pharmacology and its application to clinical practice. Selection of the subject matter and order of its presentation are based on the authors’ many years experience in teaching this material to thousands of medical, pharmacy, dental, podiatry, nursing, and other health science students.

To be as clinically relevant as possible, the book includes sections that specifically address the clinical choice and use of drugs in patients and the monitoring of their effects, and case studies that introduce clinical problems in many chapters. Presented in full color and enhanced by more than three hundred illustrations, Basic & Clinical Pharmacology features numerous summary tables and diagrams that encapsulate important information.

Coverage that spans every aspect of medical pharmacology:

  • Basic principles
  • Autonomic drugs
  • Cardiovascular-renal drugs
  • Drugs with important actions on smooth muscles
  • Central nervous system drugs
  • Drugs used to treat anemias, clotting disorders, hyperlipidemia, and inflammation and gout
  • Endocrine drugs
  • Chemotherapeutic and immunologic drugs
  • Toxicology
  • Special subjects (perinatal, geriatric, and dermatologic pharmacology)
  • Botanical and "food supplements," and over-the-counter medications
  • Prescribing

Also in this edition:

  • Drug Summary Tables conclude most chapters, providing a concise summary of the most important drugs
  • General concepts relating to newly discovered receptors, receptor mechanisms, and drug transporters
  • Descriptions of important new drugs, including monoclonal antibodies

The most trusted and up-to-date pharmacology text in medicine -- completely redesigned to make the learning process even more interesting and efficient

5 Star Doody's Review!
"This is the most widely used textbook for teaching pharmacology to health professionals. This 11th edition is far superior to any previous editions....The authors' goals are to provide a complete, authoritative, current, and readable textbook of pharmacology for students in health sciences. Testimony to their success is the widespread use of this work as required textbook for pharmacology courses around the world. This book is used extensively by thousands of medical, pharmacy, podiatry, nursing, and other health professions students to study pharmacology. Likewise, it remains a valuable resource for residents and practicing physicians....I continue to use this book as a required resource for all courses that I teach to medical, nursing, and allied health students. It is authoritative, readable, and supported by numerous learning tools."--Doody's Review Service

Organized to reflect the syllabi in Pharmacology courses, Basic & Clinical Pharmacology covers all the important concepts students need to know about the science of pharmacology and its application to clinical practice. It is acknowledged worldwide as the field’s most current, authoritative, and comprehensive textbook. To be as clinically relevant as possible, the book features a strong focus on the choice and use of drugs in patients and the monitoring of their effects.

Coverage that spans every important aspect of medical pharmacology:

  • Basic Principles
  • Autonomic Drugs
  • Cardiovascular-Renal Drugs
  • Drugs with Important Actions on Smooth Muscle
  • Drugs that Act in the Central Nervous System
  • Drugs Used to Treat Diseases of the Blood, Inflammation, and Gout
  • Endocrine Drugs
  • Chemotherapeutic Drugs
  • Toxicology

NEW to this edition:

  • Full-color presentation, including 300+ illustrations
  • Case studies introduce clinical problems in many chapters
  • Drug summary tables for key information in comparative context
  • Descriptions of important newly released drugs, including new immunopharmacologic agents
  • Expanded coverage of general concepts relating to newly discovered receptors, receptor mechanisms, and drug transporters

Integration of complementary and alternative medicine therapies (CAM) with conventional medicine is occurring in hospitals and physicians offices, health maintenance organizations (HMOs) are covering CAM therapies, insurance coverage for CAM is increasing, and integrative medicine centers and clinics are being established, many with close ties to medical schools and teaching hospitals. In determining what care to provide, the goal should be comprehensive care that uses the best scientific evidence available regarding benefits and harm, encourages a focus on healing, recognizes the importance of compassion and caring, emphasizes the centrality of relationship-based care, encourages patients to share in decision making about therapeutic options, and promotes choices in care that can include complementary therapies where appropriate.

Numerous approaches to delivering integrative medicine have evolved. Complementary and Alternative Medicine in the United States identifies an urgent need for health systems research that focuses on identifying the elements of these models, the outcomes of care delivered in these models, and whether these models are cost-effective when compared to conventional practice settings.

It outlines areas of research in convention and CAM therapies, ways of integrating these therapies, development of curriculum that provides further education to health professionals, and an amendment of the Dietary Supplement Health and Education Act to improve quality, accurate labeling, research into use of supplements, incentives for privately funded research into their efficacy, and consumer protection against all potential hazards.

Essentials of Pharmacology for Health Occupations, 6th Edition provides an extensive framework of drug information in a concise format for learners studying licensed practical nursing, medical assisting and other allied health professions. Learn calculations quickly through a simplified step-by-step process. Discover key drug information by classifications, such as their purpose, side effects, cautions, and interactions, or utilize this resource to refresh your knowledge of drugs.
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